Août 6 2020
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hps://doi.org/10.1164/rccm.200401-033OCBr J Pharmacol. N Engl J Med. Read the “Canadian Journal of Respiratory, Critical Care, and Sleep Medicine’s article, “Are the . The new recommendations follow a decade-long programme of work by GINA, prompted by concerns about the risks and consequences of the long-standing approach of commencing asthma … 2006;148(3):245–254.
Co-administration of LABA/ICS remains the most effective strategy (especially in the combination product), that allows for superior asthma control, with leukotriene antagonists and theophylline being alternate choices. In asthmatics, we should educate and reinforce the messages of appropriate treatment; intermittent treatment that is inferior is not a substitute for not educating patients on the correct way to One should note that GINA no longer publishes guidelines but rather makes recommendations – a ‘strategy’ – that allow clinicians to review the information provided and decide on management issues themselves. GINA 2019 recommendations about reliever medications in … An important recommendation is the change in treatment strategy for the management of mild asthma Background: Inhaled corticosteroids (ICSs) are the most essential medication for asthma control. Br J Clin Pharmacol. We conducted a 52-week, double-blind, multicenter trial involving patients 12 years of age or older who had mild asthma and were eligible for treatment with regular inhaled glucocorticoids. 1983;15(4):419–422. In seven trials of 6-12 months duration, patients using SMART have used quick reliever daily (weighted average 0.92 inhalations/day), have awakened with asthma symptoms once every 7-10 days (weighted average 11.5% of nights), have suffered asthma symptoms more than half of days (weighted average 54.0% of days) and have had a severe exacerbation rate of one in five patients per year (weighted average 0.22 severe exacerbations/patient/year). Die GINA-Leitlinien sind von der Global Initiative for Asthma herausgegebene Leitlinien zur Diagnostik, Einteilung und Therapie des Asthma bronchiale.. 2 Hintergrund. hps://doi.org/10.1378/chest.111.4.85211. The Global Initiative for Asthma (GINA) strives to increase awareness of asthma among health professionals, health authorities, and the general public. 3 The lowest dose (100 micrograms) of inhaled budesonide produced a more marked effect in relieving airflow obstruction, than a much larger (1600 micrograms) oral dose of the drug. Die GINA-Leitlinien werden auf der GINA-Website in Form so genannter "Pocket Guides" in mehreren Sprachen zum Download angeboten. 02:11Abstract Background Asthma exacerbations are frequent in patients with severe disease. 2020 Jan 23;7:561. doi: 10.3389/fped.2019.00561. Recent developments in the availability and use of online sources of information about asthma might add to patients' knowledge and help improve control.Aims:To investigate whether asthma control has improved by assessing levels of symptoms, exacerbations and Global Initiative for Asthma-defined control in a real-life population of patients who use the Internet and social media, as well as evaluate patient perception of control and attitudes to asthma.Methods:Online surveys were conducted among 8,000 patients with asthma (aged 18-50 years, ⩾2 prescriptions in the previous 2 years, use of social media) from 11 European countries.Results:Levels of asthma control were low: 45% of respondents had uncontrolled asthma. All rights reserved.Background:Asthma is one of the most common chronic diseases in the world, and previous studies have reported low levels of control. Results: The numbers of ED visits, admissions, and episodes of ICU care decreased during the ten years (p<0.001, p=0.033, p=0.001, respectively) while the number of ICS prescriptions increased (p<0.001). Risk of a subsequent exacerbation was determined by proportional hazard model. At present, there is no evidence that better asthma treatment outcomes can be obtained by moment-to-moment symptom-driven use of ICS/LABA therapy than conventional physician-monitored and adjusted ICS/LABA therapy.1 Budesonide is an epimeric mixture of a new synthetic non-halogenated glucocorticoid (16 alpha, 17 alpha,-(22R,S)-prophylmethylenedioxypregna-1,4-diene-11/3,21-diol-3, 20-dione). Read the “Canadian Journal of Respiratory, Critical Care, and Sleep Medicine’s article, “Are the . With respect to the mean percentage of weeks with well-controlled asthma per patient, budesonide–formoterol was superior to terbutaline (34.4% vs. 31.1% of weeks; odds ratio, 1.14; 95% confidence interval [CI], 1.00 to 1.30; P=0.046) but inferior to budesonide maintenance therapy (34.4% and 44.4%, respectively; odds ratio, 0.64; 95% CI, 0.57 to 0.73). Mild asthma imposes a substantial burden on patients, establishing the need for comprehensive management plans and ongoing support for treatment adherence. In patients with mild asthma, budesonide–formoterol used as needed was noninferior to twice-daily budesonide with respect to the rate of severe asthma exacerbations during 52 weeks of treatment but was inferior in controlling symptoms. NFA patients had higher scores for vulnerability and were most likely to admit to stress as an asthma trigger. Available from: hps://formoterol as needed in mild asthma. The overall mean number of exacerbations in the last 12 months was 0.4, with a higher frequency of exacerbations in Step 2 patients who also experienced more exacerbations requiring treatment intensification, an emergency department visit, or hospitalization.
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